Unlockable - Unlocking more duealists |
| Rex Raptor (lvl2 duelist) | Beaten all lvl 1 duelists for 3 times and have opened 5 packs of Blue eyes white dragon booster. |
| Espa Roba (lvl2 duelist) | Beaten all lvl 1 duelists for 3 times and have opened 5 packs of Red Eyes Black Dragon booster. |
| Weevil Underwood (lvl2 duelist) | Beaten all lvl 1 duelists for 3 times and have opened 5 packs of Black Skull Dragon booster. |
| Bonz (lvl2 duelist) | Beaten all lvl 1 duelists for 3 times and have opened 5 packs of Barrel Dragon booster. |
| Mako Tsunami (lvl2 duelist) | Beaten all lvl 1 duelists for 3 times and have opened 5 packs of Black Luster booster. |
| Mai Valentine (lvl 3 Duelist) | Beaten all lvl 2 duealists for 5 times and have Harpy's Feather Duster in trunk |
| Bandit Keith (lvl 3 Duelist) | Beaten all lvl 2 duealists for 5 times and have Barrel Dragon in trunk |
| Joey Wheeler (lvl 3 Duelist) | Beaten all lvl 2 duealists for 5 times and have Jinzo in trunk |
| Maximillion Pegasus (lvl 3 Duelist) | Beaten all lvl 2 duealists for 5 times and have Toon world, Toon Blue eyes and Toon Summon Skull in trunk |
| Ghoul (lvl 4 duelist) | Defeated all the lvl 3 duelists 7 times |
| Marik Ishtar (lvl 5 duelist) | Deafeat Ghouls 5 times (1 for each ghoul) |
| Arkana (lvl 4 Duelist) (Ghoul) | Defeat Marik Ishtar once |
| Rare Hunter (lvl 4 Duelist) (Ghoul) | Defeat Marik Ishtar once |
| Umbra & Lumis (lvl 4 Duelist) (Ghoul) | Defeat Marik Ishtar once |
| Strings (lvl 4 Duelist) (Ghoul) | Defeat Marik Ishtar once |
| Odion (lvl 4 Duelist) (Ghoul) | Defeat Marik Ishtar once |
| Ishizu Ishtar (lvl 5 duelist) | Defeat Marik Ishtar and Ghouls 10 times each and have a full monster deck (meaning no magic or traps in deck) |
| Kaiba (lvl 5 duelist) | Defeat Ishizu Ishtar 10 times |
| Shadi (lvl 5 duelist) | Defeat all duelists 10 times each |
| Simon | Beat all tier 5 duelists 15 times each. Duel either Anzu, Honda, or Trusdale three times in a row and on the fourth time, Simon will be unlocked. |
| Duel Computer | Beat all tier 5 duelists 15 times each. Duel Seto Kaiba three times in a row, and on the fourth time, the duel computer will be unlocked. |
| Yami Bakura | Beat all tier 5 duelists 15 times each. Duel Bakura three times in a row, and on the fourth time, Yami Bakura will appear and be unlocked. |
| Yami Marik | Beat all tier 5 duelists 15 times each. Duel Marik three times in a row, and on the fourth time, Yami Marik will appear and be unlocked. |
| Yami Yugi | Beat all tier 5 duelists 15 times each. Duel Yugi three times in a row, and on the fourth time, Yami Yugi will appear and be unlocked. |
Unlockable - Unlock New Boosters |
| Relinquished Pack | Beat Rex Raptor 10 times. |
| Toon Summoned Skull Pack | Beat Espa Roba 10 times. |
| Jinzo Pack | Beat Weevil Underwood 10 times. |
| Thousand Eyes Restrict Pack | Beat Bonz 10 times. |
| The Masked Beast Pack | Beat Mako Tsunami 10 times. |
| Zombyra the Dark Pack | Beat Mai Valentine 10 times. |
| Dark Ruler Ha Des Pack | Beat Bandit Keith 10 times. |
| Yamata Dragon Pack | Beat Joey Wheeler 10 times. |
| Guardian Sphinx Pack | Beat Maximillion Pegasus 10 times. |
| Blue Millennium Pack | Beat Rare Hunter 10 times. |
| Green Millennium Pack | Beat Strings 10 times. |
| Gold Millennium Pack | Beat Odion 10 times. |
| Purple Millennium Pack | Beat Umbra & Lumis 10 times. |
| Red Millennium Pack | Beat Arkana 10 times. |
| Green Premium Pack | Beat Simon twenty times |
| Pink Premium Pack | Beat Yami Bakura twenty times |
| Orange Premium Pack | Beat Yami Marik twenty times |
| Purple Premium Pack | Beat the Duel Computer twenty times |
| Blue Premium Pack | Beat Yami Yugi twenty times |
Glitch - Spirit Reaper Glitch |
Spirit Reaper's effect states that it cannot be destroyed as a result of battle, making it a perfect shield, but if it is targeted by a magic, trap, or monster effect card, then it is destroyed immediately (this includes equip magic cards such as United We Stand or Axe of Despair). However, if you use an equip card on Spirit Reaper, the equip magic card will be destroyed, but Spirit Reaper will remain on the field.Spirit Reaper's effect states that it cannot be destroyed as a result of battle, making it a perfect shield, but if it is targeted by a magic, trap, or monster effect card, then it is destroyed immediately (this includes equip magic cards such as United We Stand or Axe of Despair). However, if you use an equip card on Spirit Reaper, the equip magic card will be destroyed, but Spirit Reaper will remain on the field.
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