Unlockable - Unlockable Teams |
| All-Time Superstars | Win five exhibition games to unlock the Superstars Team. |
| All-Time Lakers | Win two exhibition games to unlock the All-Time Lakers |
| Hieroglyphics Team | Hold the CPU to 48 points or below and it's HIEROGLYPHICS Time. (First Time) |
| VC Team | Hold the CPU to 48 points or below and unlock the creators of the game. (Third Time) |
| 2K5 Team | Hold the CPU to 48 points or below and unlock the creators of the game. (Second Time) |
| All-time Celtics | Don't commit a foul for the entire game and unlock the All-Time Celtics. (First Time) |
| All-time Sonics | Score 127 in three consecutive games with your team and unlock the All-Time Sonics. |
| All-time 76'ers | Score 127 Total Points in one game with your team and unlock the All-Time 76'ers. |
| Sophomore Class | Hold the CPU to 48 points or below and unlock the Sophomores. (Fourth Time) |
| Rookie Class | Hold the CPU to 48 points or below and unlock the Rookies. (Fifth Time) |
| SEGA Team | Don't commit a foul for the entire game to play with the creators of the game. (Second Time) |
Unlockable - Unlockable Bobble-Heads |
| Carmelo Anthony Bobble-Head | Beat the CPU by 15 Points EACH Quarter and unlock Melo. (Second Time) |
| Lamar Odom Bobble-Head | Get 30 total assists from your team in one game and unlock 'The Goods'. (First Time) |
| Kevin Garnett Bobble-Head | Don't get blocked for an entire game and unlock KG. (First Time) |
| Elton Brand Bobble-Head | Get 25 rebounds in EACH half with your team in one game and unlock Elton Brand. (First Time) |
| Tim Duncan Bobble-Head | Get 25 rebounds in EACH half with your team in one game and unlock Tim Duncan. (Second Time) |
| Chris Webber Bobble-Head | Get 40 total rebounds from your team in one game and unlock 'C-Webb'. (Second Time) |
| Kenyon Martin Bobble-Head | Get 40 total rebounds from your team in one game to unlock Kenyon Martin. (First Time) |
| Yao Ming Bobble-Head | Block 10 shots total with your team in one game and unlock 'The Dynasty'. (First Time) |
| Ben Wallace Bobble-Head | Block 10 shots total with your team in one game and unlock 'Big Ben'. (Second Time) |
| Jason Kidd Bobble-Head | Don't get a pass intercepted for one entire game to unlock J. Kidd. (Second Time) |
| Stephon Marbury Bobble-Head | Don't get a pass intercepted for one entire game to unlock 'Starbury'. (First Time) |
| Baron Davis Bobble-Head | Make 20 three point field goals in one game with your team to unlock 'B Diddy'. |
| Kobe Bryant Bobble-Head | Make 10 Dunks in one game to unlock Kobe. (Third Time) |
| LeBron James Bobble-Head | Don't get a pass intercepted for one entire game to unlock King James. (Third Time) |
| Jermaine O'Neal Bobble-Head | Get one double double by any player on your team but one of the stats has to be above 15 to unlock Jermaine O'Neal. |
| Andrei Kirilenko Bobble-Head | Get one double double by any player on your team to unlock Andrei Kirilenko. |
| Allen Iverson Bobble-Head | Don't get blocked for an entire game and unlock 'The Answer'. (Second Time) |
| Steve Francis Bobble-Head | Get 15 total assists from your team in one game and unlock Stevie 'Franchise'. |
| Dirk Nowitzki Bobble-Head | Beat the CPU by 15 Points EACH Quarter and unlock Dirk. (First Time) |
| Peja Stojakovic Bobble-Head | Make 100% of your freethrows with your team in one game to unlock Peja. |
| Paul Pierce Bobble-Head | Score 500 Total Points and unlock 'The Truth'. (Street Games don't count) |
| Vince Carter Bobble-Head | Make 10 Dunks in one game to unlock Vince. (First Time) |
| T-Mac Bobble-Head | Make 10 Dunks in one game to unlock T-Mac. (Second Time) |
| Shaq Bobble-Head | Get one double double by any player on your team but both of the stats have to be above 15 to unlock Shaq. |
Unlockable - Unlockable Courts |
| Practice Gym Court Playable | Play 10 Street Games to unlock the Practice Gym Street Court. |
| 2K5 Street Court Playable | Play 5 Street Games to unlock the 2k5 Street Court. |
| Boss #3 Court Playable | Get 30 total assists from your team in one game and unlock a new street court. (Second Time) |
| Boss #2 Court Playable | Beat the CPU by 69 Points and unlock a new street court. A 68 point win is the current NBA record. (Second Time) |
| Boss #1 Court Playable | Beat the CPU by 69 Points and unlock a new street court. A 68 point win is the current NBA record. (First Time) |
| VC Gym Court Playable | Play 15 Street Games to unlock the VC Gym Street Court. |
Unlockable - Multiplayer 24/7 Game Modes |
| "No Blocks" in multiplayer games | Beat "No Blocks" in 24/7 mode |
| "No Steals" in multiplayer games | Beat "No Steals" in 24/7 mode |
| "Long Range Only" in multiplayer games | Beat "Long Range Only" in 24/7 mode |
| "Giant Ball" in multiplayer games | Beat "Giant Ball" in 24/7 mode |
| "Small Ball" in multiplayer games | Beat "Small Ball" in 24/7 mode |
| "Turbo Challenge" in multiplayer games | Beat "Turbo Challenge" in 24/7 mode |
