Unlockable - Unlockable Characters | |
| Karai | Beat the Foot Fight in Tournament Mode. |
| Slashuur | Beat the Battle Nexus Tournament in Tournament Mode. |
| Splinter | Beat the game and you can use Splinter in place of Donatello |
| Casey Jones | Beat the Open Brawl Tournament and Casey Jones will be playable in place of Raphael |
Unlockable - Unlock original TMNT arcade game. | |
| When on the rooftops in stage 9-1, start smashing the many crates to find an artifact. Take that artifact back home, and give it to April. Once she appraises it, she'll tell you that it is the original TMNT aracde game. Now go to the title screen, and go under options. The original TMNT arcade game will be there. | |
Unlockable - Unlock Casey Jones, Karai, Splinter and Slashuur | |
| There is another way to unblock these four characters. Beating the original TMNT Arcade Game also we will obtain to Casey Jones, Karai, Splinter and Slashuur. | |
Password - Misc. Passwords | |
| Enter the following at the password screen: | |
| Infinite Shuriken | R S R L R S M |
| Cheat Code Health | D S R D M R M |
| New Nexus outfit for Leonardo | L M R M D R D |
| Challenge Code Endurance - stamina restore no longer | M R M D R M D |
| New Nexus outfit for Raphael | R M S R M D R |
| New Nexus outfit for Michelangelo | M L M R D R M |
| New Nexus outfit for Donatello | D S L R D R M |
| Playmates added to Bonus Materials | S R M L D D R |
| Super-Tough | R D S R M R L |
| Toddling | S S S M R D D |
| Super Defense Power (Defense x2) | L D R M R L M |
| Self Recovery | D R M S R L R |
| Super Offense Power (Attack x2) | S D L S R L L |
| Squeaking | M L D S R D M |
| Poison | D R S L L S R |
| Pizza Paradise | M R L M R M R |
| Nightmare | S L S D R D L |
| Lose Shuriken | R L M R D S L |
| Fatal Blow | L R S R D R D |
| Abyss | S D S D R L D |
| Mighty Turtle | L S D R R D R |
